Introduction. West Syndrome (WS) is one of the most common causes of epilepsy in infants and young children. WS is composed of the triad of infantile spasms, an interictal electroencephalogram (EEG) pattern termed hypsarrhythmia, and mental retardation. WS is a devastating brain disorder and prognosis is one of the worst among childhood epilepsies. The purpose of the study was to elucidate the pathognomonic electroencephalographic features of WS for EE risk prediction. Material and methods. During the years 2019-2022, were examined 430 patients up to the age of 2 years, who was admitted to IMPH MCI, who presented in complains the convulsive attacks. The 16 (13,4% of them presented epileptic spasms). The patients were examined by the neurological examinations, encephalographic and neuroimaging methods (via RMN). Statistical method by simple ratio. Results. From 430 patients – 16 (3,7%, ES 0,91) of them had the complains: sudden movements in upper and lower limbs, which occurred serially on awakening, 14 (3,2%, ES 0,85) of them presented retardation in neuropsychic development, in 11 (2,5%, ES 0,75) EEG changes were suggestive for WS. Electroencephalographic results in WS showed changes: 9 (81,8%; ES 11,63) patients – typical hypsarrhythmia and 2 (18,2%, ES 11,63) patients – modified hypsarrhythmia, which are pathognomonic for WS. In one patient (9,09%, ES 8,67) MRI imaging confirmed the diagnosis of tuberous sclerosis (MRI results). Despite the treatment in some children (4 (36,36%, ES 14,50), the encephalography was continuing to be with changes. Conclusions. The results of the study shows that the SW remains one of the most common forms of epilepsy in children, which is characterized by specific clinical features and characteristic electroencephalographic tracks, which are often suggestive for developing EE risk.