Introduction: According to the latest definition of ASAM American Society of Addiction Medicine Addiction is a treatable, chronic medical disease involving complex interactions among brain circuits, genetics, the environment and an individual’s life experiences. But does the disease model explain all the reasons, why people use drugs?! Can the individual use drugs for pleasure or just as an individual choice? Aim: The objective of this work is to share different theories about the reasons why people use drugs. The aim is to focus on sociological aspects of drug use and go beyond the medical approach. Results: People use drugs to avoid pain, to seek pleasure, to manage their craving or impulsivity. On the other hand, they may choose to use drugs as a “rewording pleasure process” after a long day of work. During this work, we have gone through the history to analyze several theories of drug use as, Chicago school, Strain Theory, Deviant behavior theory or Merton theory. Many authors categorize drug use as a deviant behavior. But how difficult is to define the deviant behavior within a society’s normative system that changes continuously? Why in Albanian society is it easier to accept an alcohol user than a cannabis user? Discussion: Why people use drugs? The sociological perspective offers us many answers, but still a lot is unsaid. As far as the human nature is immense, so will be the answers.