The frequency of seizures in children with SARS-COV-2 infection
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CAPESTRU, Elena, HADJIU, Svetlana, CALCII, Cornelia, FEGHIU, Ludmila, CONSTANTIN, Olesea, ITRATUC, Irina, CALISTRU, Iulia, SPRINCEAN, Mariana, REVENCO, Ninel. The frequency of seizures in children with SARS-COV-2 infection. In: Perspectives of the Balkan medicine in the post COVID-19 era: The 37th Balkan Medical Week. The 8th congress on urology, dialysis and kidney transplant from the Republic of Moldova “New Horizons in Urology”, Ed. 37, 7-9 iunie 2023, Chişinău. București: Balkan Medical Union, 2023, Ediția 37, p. 250. ISSN Print: ISSN 1584-9244 ISSN-L 1584-9244 Online: ISSN 2558-815X.
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Perspectives of the Balkan medicine in the post COVID-19 era
Ediția 37, 2023
Congresul "Perspectives of the Balkan medicine in the post COVID-19 era"
37, Chişinău, Moldova, 7-9 iunie 2023

The frequency of seizures in children with SARS-COV-2 infection


Pag. 250-250

Capestru Elena1, Hadjiu Svetlana12, Calcii Cornelia12, Feghiu Ludmila3, Constantin Olesea1, Itratuc Irina1, Calistru Iulia1, Sprincean Mariana12, Revenco Ninel12
 
1 ”Nicolae Testemițanu” State University of Medicine and Pharmacy,
2 Institute of Mother and Child,
3 National Epileptology Center of the Republic of Moldova
 
 
Disponibil în IBN: 5 ianuarie 2024


Rezumat

Introduction. Few studies have investigated seizure prevalence and characteristics as the main symptom in children with COVID-19. The rate reported varies between 1.0 and 14.6%. The aim. To study the frequency of neurological complications in children with SARS-CoV-2 infection, and to determine the type and frequency of epileptic seizures. Material and Methods. We carried out a systematic retrospective study by analyzing the medical records of children (aged 4 months to 15 years) at the Institute of Mother and Child and the Infectious Diseases COVID-19 department from August 01, 2022, to March 01, 2023. We divided convulsive seizures into febrile and non-febrile. Results of clinical and paraclinical examinations were extracted from electronic medical records. Statistical methods used: t-student test and 95CI confidence coefficient. Results. Out of the 521 children confirmed with SARS-CoV-2 infection, 56 cases (10.7%; 95 CI 12.06-9.34) presented specific neurological complications, of which 8 (14.3%; 95 CI 18, 98-9.62) – seizures: febrile seizures at the onset of the disease – 3 (5.4%; 95CI 8.41-2.39); 5 (8.9%; 95CI 12.71-5.09), in children with pre-existing neurological disease (malformations of the central nervous system, periventricular leukomalacia, epilepsy, cerebral hypoxia, etc.). One child developed convulsive status epilepticus. In seven out of eight cases, the seizures were tonic-clonic, and in one case – focal tonic seizure. Most patients suffered from a non-severe form of COVID-19. Conclusions. Epileptic seizures may be the first manifestation of COVID-19 in children, they are often tonicclonic and can develop status epilepticus. We suggest testing the children presenting with new febrile seizures or exacerbation of previous epilepsy to recognize SARS-CoV-2 infection.