Gout and renal dysfunction
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ROTARU, Larisa, GROPPA, Liliana, CEBAN, Emil, RUSSU, Eugen, PASCAL, Rodica, SASU, Dorian, CORNEA, Cornelia. Gout and renal dysfunction. In: Perspectives of the Balkan medicine in the post COVID-19 era: The 37th Balkan Medical Week. The 8th congress on urology, dialysis and kidney transplant from the Republic of Moldova “New Horizons in Urology”, Ed. 37, 7-9 iunie 2023, Chişinău. București: Balkan Medical Union, 2023, Ediția 37, p. 170. ISSN Print: ISSN 1584-9244 ISSN-L 1584-9244 Online: ISSN 2558-815X.
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Perspectives of the Balkan medicine in the post COVID-19 era
Ediția 37, 2023
Congresul "Perspectives of the Balkan medicine in the post COVID-19 era"
37, Chişinău, Moldova, 7-9 iunie 2023

Gout and renal dysfunction


Pag. 170-170

Rotaru Larisa1, Groppa Liliana1, Ceban Emil1, Russu Eugen1, Pascal Rodica1, Sasu Dorian1, Cornea Cornelia2
 
1 ”Nicolae Testemițanu” State University of Medicine and Pharmacy,
2 Timofei Moșneaga Republican Clinical Hospital
 
 
Disponibil în IBN: 22 decembrie 2023


Rezumat

Introduction. One in 10 people with chronic kidney disease has gout, and an even higher percentage of people with gout have kidney disease [kidneyfund.org]. Objective of the study. Analysis of renal dysfunction in patients with gout in different age groups. Material and methods. 237 patients with gout (males 60 ± 8.0 years, females 63 ± 9.0 years). The patients were separated into two groups: the age of onset up to 59 years (group I, 91 people) and the age of onset after 60 years inclusive (group II, 146 people). Results. The renal function was mostly preserved in patients from group I – 51% had a level of glomerular filtration rate (GFR) corresponding to stage 2 of chronic kidney disease (CKD), stage 4 of CKD was determined in only 2 patients from group I. A pronounced decrease in kidney function was determined in group II – significantly more often there was stage 3 of CKD (16 (22%) in group I and 59 (46%) in group II, p = 0.001). In 12 participants in group II, GFR was below 29 ml/min/1.73 m2. Only in 6% of cases, a slight decrease in GFR was determined, which was 4 times lower than in group I. Conclusions. With increasing age, the frequency of risk factors for gout increases, especially for people with kidney damage: taking small doses of acetylsalicylic acid increases the risk from 6 to 40%, diuretics from 18 to 44%, alcohol consumption from 14 to 28%, hypertension from 44 to 78%, consumption of foods saturated with purine from 51 to 68%, overweightness and obesity from 58 to 76%.