The process of selecting and prioritizing investment project proposals in construction is characterized by multiple objectives and uncertainties due to incomplete information and the multitude and dynamics of factors that can intervene. Knowing their significance and influence on the final investment decision, it is a complex problem that requires a multi-critical analysis with both quantitative and qualitative factors, necessary for a good quantification and evaluation. In recent years, the increase in the complexity of projects involves a large number of factors that ensure the technical and economic success of infrastructure investments and therefore it is necessary to identify the optimal decision criteria in their selection and prioritization. Identifying and setting these criteria is generally difficult and depends on the professional skills of the project manager but should follow a systematic process to ensure its validity and transparency. The paper presents such an analysis of the Braila Bridge, which crosses the Danube River and is the largest suspended bridge in Romania and the third in Europe, which required such a study in order to benefit from the best investment decision from all points of view. Thus, two design versions with multiple and varied implications of parameters are analyzed, starting from the financial or technical one with the length of the route, the difficulty of the design and execution and especially its impact on the environment and biodiversity.