In the present study, the integrity of the action of the extracts of Nostoc halophilum and the activity of the endocrine pancreas in the case of experimental diabetes was monitored. In order to carry out rigorous research, it is necessary that following the administration of alloxan will provoke apparition of classic symptoms of the aforementioned pathology. To treat experimental diabetes the cyanobacteria water extract was used. This was obtained from the biomass of the Nostoc halophilum strain. As a rule, 2-3 days after the injection of the diabetogen, the urine was tested for glucosuria and it is considered that the animals are diabetic if this is present. But most of the time diabetes is confirmed at the end of the experiments, when the blood is collected for various tests including blood sugar. In the present study, we aimed to argue the presence of diabetes by testing several indices. During our research, a considerable increase in blood glucose level was observed in the group with experimental diabetes compared to the norm. This increase is caused by the lack of insulin. Insulin increases the permeability of the cell membrane for glucose and accelerates its passage from the intercellular fluid into the cell. In the insulin-free environment, the speed of glucose passage inside the cell is 20 times lower than in the nucleus, which contains a sufficient amount of insulin. The intensification of glucose transport through the membranes of muscle fibers and liver cells under the action of insulin favors glycogen synthesis and its accumulation in liver and muscle cells. After the administration of higher doses of insulin, a considerable amount of glucose passes through the blood plasma inside the cells of the skeletal muscles, cardiac muscle, smooth muscles, etc., because of this, the level of glucose in the blood decreases and the intake of glucose in the cells of the nervous system, on the permeability in which insulin does not work. As a result, the brain and spinal cord understand the acute insufficiency of glucose, which is the necessary source for the activity of all cells, including organs. Table 1 The level of glucose (mmol/l) after the administration of the aqueous extract of Nostoc halophilum against the background of experimental diabetes. Clues Blank Alloxan Nostoc halophilum Nostoc halophilum + Alloxan Glucose (mmol/l) 5,5±0,62 16,9±1,75 5,3±0,71 10,5±1,88 As a result (Tabel 1) of the research, it was found that the normal glucose level is 5.5 ± 0.62 mmol/l, and in the group with experimental diabetes - 16.9 ± 1.75 mmol/l. Hypoglycemic effect was observed in the group where Nostoc halophilum - 5,3±0,71(mmol/l) was administrated and in Nostoc halophilum+ Alloxan group was observed the same effect ( 10.5 ± 1.88 mmol/l), in comparison with Alloxan group (16,9±1,75).