Inflammatory bowel diseases (IBD) are characterized by a chronic inflammatory process that affects the intestinal barrier structure. Recent evidence suggests that some food components can influence the integrity of the intestinal barrier and thus its permeability. IBD is characterized by a chronic inflammatory process of the gastrointestinal tract and is marked by a disruption of the intestinal barrier with symptoms which vary from constipation, flatulence, diarrhea, reflux.In this study we wanted to see what influence certain groups of functional foods have on the intestinal flora. Laboratory Amplification of the 16S rRNA gene region using PCR with universal primers Sequence the amplified products using a high-throughput platform such as the Illumina MiSeq Analysis of sequence data using bioinformatics tools such as QIIME or Mothur,Store samples at -80°C until DNA extraction with Extract DNA from faces samples using a commercial kit or a standard protocol, Patient collection of stool samples using sterile containers and gloves.Comparison of microbial diversity and composition between different participants in the study and identifying potential associations between the gut microbiome before and after dietary intervention with functional foods, listed in the results below. For a period of 8-9 months, the dietary intervention was observed by reducing dairy products, red meat and introducing functional foods, such as listed in tabel 1 with the reduction of gastrointestinal symptoms. In conclusion, our results showed in the tabel 1, that the benefit in including and excluding, in short-term, specific food components, have potentially beneficial for IBD patients is important to improve inflamatory markers. But it is still uncertain if IBD individuals could benefit in time for reaccurence from this type of nutritional therapeutic intervention The intake/restriction of those nutrients/food did affect, in a significant way, the gut bacteria and the gastrointestinal symptomatology.