Background: The autopodium diseases at cattle remain a very little researched area in the veterinary medicine. The decrease of productive capacity and the treatment of the acropodium diseases increase the cost price of products. Knowing the sources of innervation, vascularization and the distribution areas of nerves, and the vessels which belong to the autopodium fibrous formations at cattle, has got an important role in their good functioning. These things have determined us, to realize a comprehensive study of the neuro-vascular units of fibrous formations at the metapodes of the cattles. Material and methods: Were used the cattle breeds, like the “Red of Steppe” and the “Spotted Black”, of different sex and age, wich were received from the enterprise “CARMEZ” Ltd, from Chisinau. The animals’ age was determined, based on the documents who are accompanying the cattles, from the farms which they were delivered. The anatomic study has been done by the macro-microscopic method; wich was developed by Mr. V. Vorobyov. The total periosteum preparates were stained with Shiff reagent. Results: The periosteum bones of metapodes at bovines present a well-developed nervous apparatus. To periosteum nerve branches come directly from regional nerves. In periosteum, the nerves have a oblique orientated traject, relative to the longitudinal axis of metapodes. Into the adventiceal layer the nerves are forming a polygonal wide network, and the blood vessels – small nettings. Other nervous trunks provide small nervous branches for the adventiceal plexuses and then they penetrate deeply the fibroelastic layer. A third part of nerves, which penetrate the superficial and deep layers of the periosteum, and therefore, penetrate the bone. Conclusions: The periosteum of the metacarpal and metatarsal bones has a specific innervation. The abundance of neurovascular elements indicate a functional importance of these autopodium segments wich support a major physical load and provide synchronization of the thoracic and pelvic limbs activity.