Mолекулярная эволюция, филогения и стратегия эволюционного анализа белков

Шутов Андрей; Kahovscaia Irina; Рудакова Анжела; Laptev Natalia; Shallau Anna

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2023-05-30 19:33

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ШУТОВ, Андрей, KAHOVSCAIA, Irina, РУДАКОВА, Анжела, LAPTEV, Natalia, SHALLAU, Anna. Mолекулярная эволюция, филогения и стратегия эволюционного анализа белков. In: Studia Universitatis Moldaviae (Seria Ştiinţe Reale şi ale Naturii), 2010, nr. 6(36), pp. 5-8. ISSN 1814-3237.

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Studia Universitatis Moldaviae (Seria Ştiinţe Reale şi ale Naturii)

Numărul 6(36) / 2010 / ISSN 1814-3237 /ISSNe 1857-498X

Mолекулярная эволюция, филогения и стратегия эволюционного анализа белков

Pag. 5-8

Шутов Андрей, Kahovscaia Irina, Рудакова Анжела, Laptev Natalia, Shallau Anna

Молдавский Государственный Университет

Disponibil în IBN: 14 decembrie 2013

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În lucrare este prezentată o strategie raţională de analiză a evoluţiei unei familii de proteine, bazată pe orientarea succesiunilor de aminoacizi componenţi. Principiile de bază ale strategiei sunt axate pe alegerea celor mai adecvate regiuni de succesiuni, a seturilor de succesiuni şi a derivaţilor succesiunilor. Eficacitatea strategiei a fost demonstrată prin studierea evoluţiei familiei de proteine Ariadne Ring-Ibr-Ring şi compararea cu datele publicate de alţi autori.

An expedient strategy for evolutionary analysis of protein families based on alignment of their amino acid sequences is described. General principles of the strategy consists of selection of most suitable sequence region, sequence set and out-group sequences. The efficiency of the strategy was demonstrated using evolutionary analysis of Ariadne family of Ring-IBR-Ring proteins in comparison with the data previously published by other authors.

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