The article compared different countries in the world on the fundamental pillars that define the digital quality of life. The DQL index is analyzing the impact of five basic pillars: internet accessibility, connection quality, e-infrastructure, digital security, and e-government. In 2021 the top of the DQL index is Denmark, followed by South Korea, Finland, Israel, USA, Singapore, France, Switzerland, Germany, UK, Netherlands, Japan, Sweden, and Lithuania. The global Digital Quality of Life (DQL) index calculated for 110 countries in the world and covering 90% of the world's population, shows an increase in digital quality of life in the Republic of Moldova in 2021 compared to the previous year. The Republic of Moldova ranks 50th out of 110 countries in the world and 32nd in Europe from 38 countries, with an increasing index compared to 2020. Moldova’s rank of internet accessibility is 18, connection quality - 35, e-infrastructure - 66, digital security - 52 and e-government 65.This paper has been developed within the framework of the Scientific Project for the period 2020-2023, registered in the State Register of projects in the field of science and innovation of the Republic of Moldova with the code 20.80009.0807.29 Proiect Program de Stat ”Perfecționarea mecanismelor de aplicare instrumentelor inovaționale orientate spre creșterea durabilă a bunăstării populației Republicii Moldova” / Project State Program ”Improving the mechanisms for applying innovative instruments aimed at sustainably increasing the welfare of the population of the Republic of Moldova”.