Although the meaning of the word dynasty refers to a family whose members "inherit the succession to the leadership of a state" (DEX), the second explanation is "a succession of personalities of the same family." In this case I would make a difference between dynasty, whose members succeed each other for at least three generations and families whose members are brothers, parents and children, uncles and grandchildren, cousins, etc., so they are part of the same generation or two respectively. Many families of musicians are known in the history of music whose contribution through their talent, mastery and devotion occupies an important place in the evolution of the art of sounds such as: Couperin, Bach, Hartmann, Stamitz, Kozeluch, Strauss etc. In Romania there are known families of musicians such as Caudella, Dumitrescu, Mandisevschi, Burada, Wachmann, Gheorghiu, etc. In the Republic of Moldova, through the personal contribution to the composition and performing arts, the Neaga, Bivol, Rusnac, Buinovschi families stood out. The purpose of this article is to provide an overview of the members of the Caftanat, Pocitari, Botgos, Ștefaneț, Advahov dynasties, to note the plurivalence and main features of their art activity and to analyze the similarities and differences between families, while synthesizing the information obtained. The text will contain brief biographical details about each one, the focus being, however, on the important achievements of the most representative members.