Environmental pollution affects population health depending on the extension and the degree of exposure to environmental factors. In most cases it is difficult to obtain an accurate situation of exposure of population to harmful factors. Health status is determined by: human biology, ecological factors, the socio-economic situation of each person and the quality of medical services. According to regional, the interdependence of those factors could vary, but not significantly. The environmental risks are everywhere, but diminishing them may improve the health status of the population. The main diseases, registered on the territory Northern Development Region of the Republic of Moldova, during the 2010‒2019 years, are: cardiovascular diseases – 25,0%; respiratory system diseases – 20,0% and digestive diseases – 11%.