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SM ISO690:2012 DICUSAR, Olga, MUNTEANU (IVANOV), Mihaela, CIOBANU, Lucia, IVANOV, Victoria, POPOVICI, Mihail. Sex differences in the clinical presentation and management of patients with non-st-segment elevation myocardial infarction. In: Cercetarea în biomedicină și sănătate: calitate, excelență și performanță, Ed. 1, 20-22 octombrie 2021, Chişinău. Chișinău, Republica Moldova: 2021, p. 123. ISBN 978-9975-82-223-7 (PDF).. |
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Cercetarea în biomedicină și sănătate: calitate, excelență și performanță 2021 | ||||||
Conferința "Cercetarea în biomedicină și sănătate: calitate, excelență și performanță" 1, Chişinău, Moldova, 20-22 octombrie 2021 | ||||||
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Background. Despite the fact that women have lower incidence of NSTEMI compared with men, they have a higher mortality, are older and have an increased risk profile. At the same time, they more often report atypical symptoms and benefit less from invasive strategies compared to men. Objective of the study. Assessment of gender differences in the clinical presentation, management and mortality of patients presenting with NSTEMI in the Republic of Moldova. Material and Methods. Data were collected from the observational studies: retrospective (2019) and prospective (2020-2021), conducted in 3 PCI centers in Moldova, which included 351 consecutive patients with the clinical diagnosis NSTEMI. A questionnaire with 178 questions was completed, and the data obtained were processed by descriptive statistical methods, the Pearson χ² test and the p-value were used. Results. Women with NSTEMI were fewer than men: 38.2%, but had a higher rate of most risk factors: hypertension- 96.3% vs 87.6% (χ² 9.0, p <0.05), hypercholesterolemia- 66.4% vs 63.9% (χ² 4.2, p <0.05), diabetes - 44.8% vs 33.6% (χ² 0.35, p> 0.05), except smoking: 3.7% vs 27.9% (χ² 59.3, p <0.001). They presented with more advanced heart failure: Killip III-IV 26.6% vs 13.8% (χ² 9.5, p <0.05) . Non-obstructive coronary arteries were seen more frequently on coronary angiography: 15.8% vs 3.6% (χ² 14.7, p <0.05). Women were less likely than men to undergo PCI 67.4% vs 77.7% ( χ² 1.7, p> 0.05) and showed a higher in-hospital mortality: 11.6% vs 6.8% (χ² 2.07, p> 0.05). Conclusion. Compared to men, women had a lower incidence of NSTEMI, but had a higher rate of risk factors, more often reported atypical symptoms and advanced heart failure. Non-obstructive coronary arteries were seen more frequently and benefitted less from PCI, and in-hospital mortality was higher |
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Cuvinte-cheie myocardial infarction without ST-segment elevation, women, infarct miocardic, elevarea segmentului ST, femei |
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