Articolul precedent |
Articolul urmator |
282 5 |
Ultima descărcare din IBN: 2022-05-06 20:28 |
SM ISO690:2012 CIORNOLUȚCHII, Vera, COREŢCHI, Ianoş. Complications of antibacterial drug therapy. In: Cercetarea în biomedicină și sănătate: calitate, excelență și performanță, Ed. 1, 20-22 octombrie 2021, Chişinău. Chișinău, Republica Moldova: 2021, p. 28. ISBN 978-9975-82-223-7 (PDF).. |
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Cercetarea în biomedicină și sănătate: calitate, excelență și performanță 2021 | ||||||
Conferința "Cercetarea în biomedicină și sănătate: calitate, excelență și performanță" 1, Chişinău, Moldova, 20-22 octombrie 2021 | ||||||
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Rezumat | ||||||
Background. Antibacterial drugs are widely used worldwide. The demonstration of the particularities of the risks associated with their administration and the application of their prophylaxis measures determine the increase of the efficacy and inoffensiveness of the treatment. Objective of the study. Elucidation of the peculiarities of the complications of antimicrobial therapy and identification of their prophylaxis actions. Material and Methods. From the PubMed and Scopus databases, the articles published during the years 2010-2020 were selected, according to the keywords: antimicrobials, side effects, complications. In addition, we used clinical pharmacology books to select and process information about the complications of antibacterial drug therapy. Results. The main risk factors that may influence the occurrence and severity of complications of antimicrobial therapy are age, pregnancy, and lactation, liver and kidney function, allergy or intolerance, recent use of antimicrobial drugs, polypragmasy, drug interactions. The mechanisms by which antimicrobials can worsen the condition of patients suffering from various pathologies range from direct toxicity to dysbiosis, immunosuppression, idiosyncratic reactions, as well as the selection of resistant bacteria. Early diagnosis of the side effects of antimicrobials allows to avoid or minimize further complications. Conclusion. Knowing the risk factors and mechanisms of developing of complications of antibacterial therapy allows the implementation of strategies to minimize them, based on compliance with the principles of rational antibacterial therapy. |
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Cuvinte-cheie complications, antibacterials, side effects, complicaţii, Antibacteriene, reacţii adverse |
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