Veterinary drugs are widely used in raising animals and birds in preventing diseases that may occur, for treatments, but also for increasing muscle mass. If administration doses and waiting periods are not observed, residues may be detected in foodstuffs obtained from them. The competent authorities of the Republic of Moldova are responsible for monitoring the use of substances for this purpose and apply systematic controls and monitoring programs to determine compliance with the provisions of legislative acts and to know the situation in the field. For the regulation of residues of various veterinary medicinal substances, by experts and specialists with competence in the field, rules and limits have been developed and adopted by regulatory documents as directives, regulations. The given documents have been published and proposed for use in all countries wishing to be governed by them. In this study, we are performed on regulatory acts in the Republic of Moldova on residues of veterinary drugs in food of animal origin and the specific requirements of certain groups of substances with a major impact on consumer health. The current information of modification or change in the context of the new requirements is presented, as well as the planned implementation stage.