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SM ISO690:2012 MIHALCEANU, Luminiţa, CAPROS, Hristiana, SURGUCI, Mihail, COJOCARI, Nina. Colestaza gravidelor: rezultate perinatale. In: Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, 21-23 octombrie 2020, Chişinău. Chişinău: USMF, 2020, p. 605. |
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Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” 2020 | ||||||
Congresul "Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”" Chişinău, Moldova, 21-23 octombrie 2020 | ||||||
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Pag. 605-605 | ||||||
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Rezumat | ||||||
Background. Also called ictus gravidarum, intrahepatic cholestasis of pregnancy is a histological lesion without inflammation or proliferation of mesenchymal cells and can have a significant impact on fetal morbidity, especially after 36 weeks of gestation. Objective of the study. Evaluation of the peculiarities of the evolution of pregnancy, maternal and fetal complications in case of intrahepatic cholestasis of pregnancy. Material and Methods. It is a case-control study conducted in the period of 2015-2019 in which the evolution of pregnancy and perinatal outcomes in pregnant women with cholestasis were compared compared to pregnant women with physiological pregnancy after 36 weeks of gestation hospitalized in SCM no. 1. Results. It were analyzed 42,678 obstetric files. The incidence of cholestasis in pregnancy accounted for 0.7% of the total number of births. According to the study, cholestasis of pregnancy was found more frequently in women with BMI> 35 kg / m2 (10.6% versus 5.5%, p <0.001), in those with diabetes (25.7% versus 9.8%, p <0.001) and in those with twin pregnancies (8.7% versus 2.2%, p <0.001). The most common complications in pregnant women with cholestasis included premature births, with a mean gestational age of 36.4 weeks compared to the term of pregnancy of 38.6 weeks in the control group (p <0.001), low birth weight (3.12 versus 3.31 kg, p < 0.001), and the increased need for care of the newborn in the intensive care unit (44.5% versus 15.3%, p <0.001). Conclusion. In case of cholestasis of pregnancy in the baseline group, the correct behavior consequently had the same results of perinatal mortality, but newborns from mothers with cholestasis of pregnancy more requently needed specialized neonatal care compared to the control group. |
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Cuvinte-cheie intrahepatic cholestasis of pregnancy, liver function tests, pruritus, colestaza gravidelor, teste hepatice funcționale, prurit |
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