Articolul precedent |
Articolul urmator |
409 6 |
Ultima descărcare din IBN: 2022-06-27 11:52 |
SM ISO690:2012 MUNTEANU, Oxana, RUSU, Doina, TAMBALA, Diana, BOTNARU, Victor. Bronșiectaziile la pacienții adulți cu infecție hiv/sida: serie de cazuri. In: Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, 21-23 octombrie 2020, Chişinău. Chişinău: USMF, 2020, p. 296. |
EXPORT metadate: Google Scholar Crossref CERIF DataCite Dublin Core |
Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu” 2020 | ||||||
Congresul "Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”" Chişinău, Moldova, 21-23 octombrie 2020 | ||||||
|
||||||
Pag. 296-296 | ||||||
|
||||||
Descarcă PDF | ||||||
Rezumat | ||||||
Background. Immunodeficiencies should be suspected in cases of primary identified bronchiectasis in adults. Moldova is among countries with a continuous increase in the number of HIV-infected adults. Impaired immune system and chronic inflammation contribute to the progression of bronchiectasis in HIV patients. Objective of the study. To present the clinical, imaging, bacteriological peculiarities and outcomes in adult patients with bronchiectasis and HIV/AIDS infection. Material and Methods. This case series involved 11 patients with HIV/AIDS and bronchiectasis, selected from a prospective study on 490 patients diagnosed with non-cystic fibrosis bronchiectasis in a tertiary care hospital, between 2015–2019. Clinical, microbiological and radiological data, alongside, comorbidities and severity scores were analysed. Statistical analysis was performed using the SPSS 23 program. Results. The mean age was 39 years (range 25-65 years), with a male predominance (54%). A CD4 count <200 cells/mm3 was identified in 6 cases. The mReiff score (6.8±4.6) showed a significant correlation with Bhalla score (9.72±4.5), r=0.66 (p<0.05). BSI score (11.7±3) reflects better the severity of the disease, showing a significant correlation with the Bhalla imaging score (r=0.62, p<0.05). Assessing the impact of comorbidities (BACI index 5.4±4.3 and Charlson index 6.9±1.3), the BACI index better reflected the severity of the disease in this group of patients, demonstrating a strong correlation with BSI (r =0.62, p<0.05). Only 3 patients (27%) were alive after one year of follow-up. Conclusion. Bronchiectasis is one of the common pulmonary manifestations of HIV/AIDS infection, being responsible for a number of chronic respiratory symptoms and the risk of premature death. |
||||||
Cuvinte-cheie bronchiectasis, HIV/AIDS, mReiff score, Bhalla score, BACI index, Bronşiectazii, HIV/SIDA, scorul mReiff, scorul Bhalla, indicele BACI |
||||||
|
Cerif XML Export
<?xml version='1.0' encoding='utf-8'?> <CERIF xmlns='urn:xmlns:org:eurocris:cerif-1.5-1' xsi:schemaLocation='urn:xmlns:org:eurocris:cerif-1.5-1 http://www.eurocris.org/Uploads/Web%20pages/CERIF-1.5/CERIF_1.5_1.xsd' xmlns:xsi='http://www.w3.org/2001/XMLSchema-instance' release='1.5' date='2012-10-07' sourceDatabase='Output Profile'> <cfResPubl> <cfResPublId>ibn-ResPubl-125811</cfResPublId> <cfResPublDate>2020</cfResPublDate> <cfStartPage>296</cfStartPage> <cfISBN></cfISBN> <cfURI>https://ibn.idsi.md/ro/vizualizare_articol/125811</cfURI> <cfTitle cfLangCode='RO' cfTrans='o'>Bronșiectaziile la pacienții adulți cu infecție hiv/sida: serie de cazuri</cfTitle> <cfKeyw cfLangCode='RO' cfTrans='o'>bronchiectasis; HIV/AIDS; mReiff score; Bhalla score; BACI index; Bronşiectazii; HIV/SIDA; scorul mReiff; scorul Bhalla; indicele BACI</cfKeyw> <cfAbstr cfLangCode='EN' cfTrans='o'><p>Background. Immunodeficiencies should be suspected in cases of primary identified bronchiectasis in adults. Moldova is among countries with a continuous increase in the number of HIV-infected adults. Impaired immune system and chronic inflammation contribute to the progression of bronchiectasis in HIV patients. Objective of the study. To present the clinical, imaging, bacteriological peculiarities and outcomes in adult patients with bronchiectasis and HIV/AIDS infection. Material and Methods. This case series involved 11 patients with HIV/AIDS and bronchiectasis, selected from a prospective study on 490 patients diagnosed with non-cystic fibrosis bronchiectasis in a tertiary care hospital, between 2015–2019. Clinical, microbiological and radiological data, alongside, comorbidities and severity scores were analysed. Statistical analysis was performed using the SPSS 23 program. Results. The mean age was 39 years (range 25-65 years), with a male predominance (54%). A CD4 count <200 cells/mm3 was identified in 6 cases. The mReiff score (6.8±4.6) showed a significant correlation with Bhalla score (9.72±4.5), r=0.66 (p<0.05). BSI score (11.7±3) reflects better the severity of the disease, showing a significant correlation with the Bhalla imaging score (r=0.62, p<0.05). Assessing the impact of comorbidities (BACI index 5.4±4.3 and Charlson index 6.9±1.3), the BACI index better reflected the severity of the disease in this group of patients, demonstrating a strong correlation with BSI (r =0.62, p<0.05). Only 3 patients (27%) were alive after one year of follow-up. Conclusion. Bronchiectasis is one of the common pulmonary manifestations of HIV/AIDS infection, being responsible for a number of chronic respiratory symptoms and the risk of premature death.</p></cfAbstr> <cfAbstr cfLangCode='RO' cfTrans='o'><p> </p><p>Introducere. Imunodeficiențele trebuie suspectate la pacienții adulți primar identificați cu bronșiectazii. Moldova se regăsește printre țările cu o creștere continuă a numărului de adulți HIV infectați. Sistemul imun compromis și inflamația cronică contribuie la progresarea bronșiectaziilor la pacienții cu HIV. Scopul lucrării. Prezentarea particularităților clinice, imagistice, bacteriologice și evolutive la pacienții adulți cu bronșiectazii și infecție HIV/SIDA. Material și Metode. O serie de 11 cazuri cu infecție HIV/SIDA și bronșiectazii selectați din studiul prospectiv cu un lot de 490 pacienți adulți cu bronșiectazii non fibroză chistică evaluați într-un spital de nivel terțiar în perioada 2015-2019. Au fost analizate datele clinice, microbiologice, comorbiditățile, scorurile imagistice și de severitate. Datele au fost prelucrate în programul SPSS versiunea 23. Rezultate. Vârsta medie a fost de 39 de ani (28-74), cu predominanță masculină (54%). În 6 cazuri a fost identificat un nivel CD4+ <200 celule/mm3. Scorul mReiff (6.8±4.6) a demonstrat o corelație puternică cu scorul Bhalla (9.72±4.5) cu r=0.66 (p<0.05). Scorul BSI reflectă mai bine severitatea bolii, demonstrând o corelație bună cu scorul imagistic Bhalla (r=0.62, p<0.05). Evaluând impactul comorbidităţilor (indicele BACI 5.4±4.3 și indicele Charlson 6.9±1.3), indicele BACI a reflectat mai bine severitatea bolii în acest grup de pacienți, demonstrând o corelație puternică cu scorul BSI (r = 0.62, p<0.05). Doar 3 pacienți (27%) au supraviețuit la 1 an de la includerea în studiu. Concluzii. Bronșiectaziile sunt printre manifestările pulmonare frecvente ale infecției HIV/SIDA, fiind responsabile de o serie de simptome respiratorii cronice și riscul unui deces prematur.</p></cfAbstr> <cfResPubl_Class> <cfClassId>eda2d9e9-34c5-11e1-b86c-0800200c9a66</cfClassId> <cfClassSchemeId>759af938-34ae-11e1-b86c-0800200c9a66</cfClassSchemeId> <cfStartDate>2020T24:00:00</cfStartDate> </cfResPubl_Class> <cfResPubl_Class> <cfClassId>e601872f-4b7e-4d88-929f-7df027b226c9</cfClassId> <cfClassSchemeId>40e90e2f-446d-460a-98e5-5dce57550c48</cfClassSchemeId> <cfStartDate>2020T24:00:00</cfStartDate> </cfResPubl_Class> <cfPers_ResPubl> <cfPersId>ibn-person-18864</cfPersId> <cfClassId>49815870-1cfe-11e1-8bc2-0800200c9a66</cfClassId> <cfClassSchemeId>b7135ad0-1d00-11e1-8bc2-0800200c9a66</cfClassSchemeId> <cfStartDate>2020T24:00:00</cfStartDate> </cfPers_ResPubl> <cfPers_ResPubl> <cfPersId>ibn-person-12017</cfPersId> <cfClassId>49815870-1cfe-11e1-8bc2-0800200c9a66</cfClassId> <cfClassSchemeId>b7135ad0-1d00-11e1-8bc2-0800200c9a66</cfClassSchemeId> <cfStartDate>2020T24:00:00</cfStartDate> </cfPers_ResPubl> <cfPers_ResPubl> <cfPersId>ibn-person-83254</cfPersId> <cfClassId>49815870-1cfe-11e1-8bc2-0800200c9a66</cfClassId> <cfClassSchemeId>b7135ad0-1d00-11e1-8bc2-0800200c9a66</cfClassSchemeId> <cfStartDate>2020T24:00:00</cfStartDate> </cfPers_ResPubl> <cfPers_ResPubl> <cfPersId>ibn-person-11676</cfPersId> <cfClassId>49815870-1cfe-11e1-8bc2-0800200c9a66</cfClassId> <cfClassSchemeId>b7135ad0-1d00-11e1-8bc2-0800200c9a66</cfClassSchemeId> <cfStartDate>2020T24:00:00</cfStartDate> </cfPers_ResPubl> </cfResPubl> <cfPers> <cfPersId>ibn-Pers-18864</cfPersId> <cfPersName_Pers> <cfPersNameId>ibn-PersName-18864-2</cfPersNameId> <cfClassId>55f90543-d631-42eb-8d47-d8d9266cbb26</cfClassId> <cfClassSchemeId>7375609d-cfa6-45ce-a803-75de69abe21f</cfClassSchemeId> <cfStartDate>2020T24:00:00</cfStartDate> <cfFamilyNames>Munteanu</cfFamilyNames> <cfFirstNames>Oxana</cfFirstNames> </cfPersName_Pers> </cfPers> <cfPers> <cfPersId>ibn-Pers-12017</cfPersId> <cfPersName_Pers> <cfPersNameId>ibn-PersName-12017-2</cfPersNameId> <cfClassId>55f90543-d631-42eb-8d47-d8d9266cbb26</cfClassId> <cfClassSchemeId>7375609d-cfa6-45ce-a803-75de69abe21f</cfClassSchemeId> <cfStartDate>2020T24:00:00</cfStartDate> <cfFamilyNames>Русу</cfFamilyNames> <cfFirstNames>Д.</cfFirstNames> </cfPersName_Pers> </cfPers> <cfPers> <cfPersId>ibn-Pers-83254</cfPersId> <cfPersName_Pers> <cfPersNameId>ibn-PersName-83254-2</cfPersNameId> <cfClassId>55f90543-d631-42eb-8d47-d8d9266cbb26</cfClassId> <cfClassSchemeId>7375609d-cfa6-45ce-a803-75de69abe21f</cfClassSchemeId> <cfStartDate>2020T24:00:00</cfStartDate> <cfFamilyNames>Tambala</cfFamilyNames> <cfFirstNames>Diana</cfFirstNames> </cfPersName_Pers> </cfPers> <cfPers> <cfPersId>ibn-Pers-11676</cfPersId> <cfPersName_Pers> <cfPersNameId>ibn-PersName-11676-2</cfPersNameId> <cfClassId>55f90543-d631-42eb-8d47-d8d9266cbb26</cfClassId> <cfClassSchemeId>7375609d-cfa6-45ce-a803-75de69abe21f</cfClassSchemeId> <cfStartDate>2020T24:00:00</cfStartDate> <cfFamilyNames>Ботнару</cfFamilyNames> <cfFirstNames>В.</cfFirstNames> </cfPersName_Pers> </cfPers> </CERIF>