The main aim of the research evaluation of flood runoff of the Cubolta river located in the northern part of the Republic of Moldova. The Cubolta river length is 109 km and basin are is of 869 km2. Flood runoff temporal and spatial distribution, its evolution and change is analyzed and described. The time series of the flood characteristics are represented by the information monitored at Cubolta hydrological station for 1966-2012. Average maximal discharge is 13.3 m3/s, flood depth - 4.46 mm, volume -3.9 mil. m3, total flood duration - 10 day, increasing faze is 3.7 days. General trend for peak discharge is decreasing and for flood runoff depth is increasing. The largest floods occurred in 1985, 1971, 1987. Spatial distribution of flood runoff and its changes due to land use management activities from the last 3 decades was performed using SCS-CN model. Flood runoff modeling was performed for ungauged tributaries of the Cubolta river in condition of equal rainfall of 100 mm, land cover for 1982 and 2013 and 3 soil moisture conditions: dry, wet and average. Average modeled flood runoff values are 61 mm, 30 mm in case of dry soil and 85 in case of wet soils. General dynamics shows that for the last 3 decades the flood runoff has slightly decreased.