The research of metals in the "water-suspension-sediment" system in the lower part of the river allow evaluating the processes that take place in the river basin and to assess the migration variability and pollution level of the Dniester estuary and the Black Sea coast, adjacent to the estuary. The main objective of the paper was to assess the dynamics of metals, especially heavy metals, their ratio in the water-suspension-sediment system and assess the pollution level of water and bottom sediments with heavy metals in the lower Dniester, in accordance with the requirements of the Water framework Directive 2000/60/EC. The joint monitoring also aimed to test the methods of collection and analysis of metals in aquatic ecosystems used by the Institute of Zoology, Chisinau, Republic of Moldova and SRI Ukrainian Scientific Center of Ecology of the Sea, svetakovalish@gmail.com, Odessa, Ukraine in project BSB165 - HydroEcoNex and BSB 27 -MONITOX. The samples were collected at 55 and 51 km upstream of the confluence of the Dniester with the estuary. The water samples were filtered directly in the field through membrane filters with a pore diameter of 0.45 microns to detect suspensions using the Sartorius filter system. For the analysis of sediments layers of up to 3-5 cm were collected. The following equipment was used to analyze the content of metals and trace elements: • Thermo Scientific iCAP 6000 Inductively Coupled Plasma Optical Emission Spectrometer (ICP-OES), • Perkin Elmer AAnalyst 400 atomic absorption spectrometers, • Atomic-absorption spectrophotometer AAS «ZEEnit 650P», • Plasma spectrophotometer AAS «Spectr-AA-220» (Varian). The content of macro- and trace elements was analyzed: Ca, Mg, Mn, Na, K, Ba, Al, Li, Sr, Be, Bi, Cd, Cr, Co, Cu, Hg, Fe, Ar, Pb, V, Mo, Ni, Zn, Sb, Tl and some metalloids and non-metals. The content of metals in the analysed samples of water varied within a wide range, but no concentrations exceeding water quality category III (moderately polluted) was detected. It should be noted that the concentration of metals in suspensions, compared to previous years is considerable lower than the concentrations of dissolved metals which is not characteristic for the rivers and is related to the low concentration of suspensions in water. The dynamics of some metals in sediments exceeded the content in the soils of the given region.