The coordination chemistry of the transition metal complexes with
thiosemicarbazide derivatives has been widely investigated due to their attractive
chemical, physical and biological properties. Employing various thiosemicarbazide
derivatives and different metal ions with different oxidation states allows the preparation
of a wide number of coordination compounds with original structures and properties.
In this work we present a new way of activation of the thiosemicarbazide fragment
and his condensation product with salicylaldehyde - thiosemicarbazone by coordination
to the transition metals. An interesting point is to functionalize the salicylaldehyde
thiosemicarbazone with strong ionic group to increase the solubility in water of products.
For this, we functionalize the five positions of the salicylic fragment by cationic
groups like N+(CH3)3 and anionic groups like NaSO3
. First, was synthesized the
corresponding salicylic aldehyde, and after his condensation products with N4 -
substituted thiosemicarbazide was performed.
The obtained ligands were used for the synthesis of new coordination compounds with 3D transition
metals.
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