This study addresses a current issue concerning spatial and temporal analysis of Moldova's climate resources and is intended for the use of people involved in various tourism and related activities. For researchers in the field, the study will be a source of information, allowing comparison of the results obtained for other locations, and for practitioners an indispensable working tool. The motivation for the present study resides in the sparseness and ambiguity of the analysis of climate resources for tourism included in the assessment of the natural tourism potential of Romania. We aim to improve this approach by constructing for Moldova a statistically relevant, quantitative analysis of what climate offers the tourists. To achieve the proposed objectives, we used TCI and a climate database sufficiently detailed to capture climate patterns up to ten-days time intervals. We showed that in Moldova the May-September interval is the most favorable for developing all forms of tourism. We then customized the analysis at the level of each tourism resort. Our study is among the first in this region to use such analysis and provides clear research results to those involved in tourism to improve their decision-making process. The results are very important in supporting tourism in Moldova and will contribute to raising the economic potential of the region.