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SM ISO690:2012 EŢCO, Ludmila, CHIRIAC, Ala. Metoda expres-analizei variabilităţii ritmului cardiac la gravide cu iminenţă de întrerupere a sarcinii. In: Sănătate Publică, Economie şi Management în Medicină , 2012, nr. 4(43), pp. 16-21. ISSN 1729-8687. |
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Sănătate Publică, Economie şi Management în Medicină | ||||||
Numărul 4(43) / 2012 / ISSN 1729-8687 /ISSNe 2587-3873 | ||||||
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Pag. 16-21 | ||||||
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The threat of premature birth is one of the major problems of modern obstetrics and perinatology. Its frequency varies from 10 to 25%, including 5-10% of premature births. The share of preterm babies accounts for more than 50% of stillbirths, 70-80% of early neonatal mortality, and infant mortality rate of 60-70%. The clinical diagnosis of threatened preterm labor is diffi cult, it is often delayed, and therapeutic measures based on it are excessive or ineffi cient. During their stay in the hospital, all pregnant women carried out equal and standard treatment for threatened abortion. Currently, for the diagnosis of preterm labor it is suggested a number of biochemical markers (determination of fibronectin in cervical-vaginal secretions, interleukins 6 and 8 in the amniotic fl uid), instrumental techniques (transvaginal ultrasound measurement of cervical length), and others. Meanwhile, current prediction methods must meet the requirements of not only high reliability but also simplicity, the small amount of time on their conduct, to give an opportunity to evaluate the mechanisms of regulation of the whole organism of pregnant and refl ect the individual characteristics of functioning at that level in real time. The article is devoted to the justifi cation of the need to use (including outpatient) of integrated computer studies «Omega-M», for the rapid diagnosis of functional body state of women with threatened abortion, by mathematical analysis of heart rate variability. The possibility of applying a set of «Omega-M» to assess the functional state of the organism at different levels of control (vegetative, neuro-humoral, center), the adaptivecompensatory capacity and functional reserves of the woman with the threat of miscarriage in real time at the level of the whole organism. According to our results of cardiointervalography we found that only in 14,8 ± 6,9% of cases the functional state of the organism of pregnant women with the threat of termination of pregnancy corresponded to the norm (integral indicator of health Health corresponded to 70,5 ± 8,9%). In 85,2 ± 7,5% of cases, this indicator varied from 6 to 69%, whereas normally, this rate should correspond to 60-100%. The literature data and preliminary results we obtained demonstrate non-invasive and safe for both mother and fetus of the method of rapid diagnosis of heart rate variability of pregnant by cardiointervalography,suitable for monitoring the functional status of patients on an outpatient basis, while the use of complex biochemical, immunological, functional, and other special methods for assessing the adaptive-compensatory abilities of the body is possible only in specialized clinical settings. For a large introduction to the obstetric practice of the mathematical method of research, a differentiated approach of treatment is necessary to continue the longitudinal study during pregnancy. |
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Cuvinte-cheie threat of pregnancy interruption, heart rate variability, cardiointervalography, functional body state at pregnant women, угроза прерывания беременности, вариабельность ритма сердца, кардиоинтервалография, функциональное состояние организма беременной |
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