The article elucidates the phenomenon of suicide in Republic of Moldova and present factors which determining adolescents to recourse to such actions. The theoretical value and practical value of research lies in delimiting the theoretical framework of analysis and research of the determinant factors that lead to suicide by integrating theories of sociology, the testing of quantitative and qualitative research tools of suicide among adolescents in Moldova. The results of investigations enrich the theoretical fondations of sociological knowledge with new extensive knowledge about phenomenon which is quite widespread in Republic Moldova, especially in recent years.