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638.135:[543.4+615.32] (1) |
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SM ISO690:2012 POGREBNOI, Serghei, EREMIA, Nicolae, BILAN, Dmitri, LUPAŞCU, Lucian, BOLOCAN (SECARA), Natalia, DUKA, Gh., ARMAŞU, Svetlana, TERTEAC, Dumitru, CEBANU, Vitalie, TINCU, Serghei, ZNAGOVAN, Alexandru, MIHAILOVA (NEICOVCENA), Iulia, COȘELEVA, Olga, SLANINA, Valerina, MAKAEV, Fliur. Characterization of propolis from Moldova's central region: chemical composition, antioxidant and antimicrobial properties. In: Chemistry Journal of Moldova, 2023, nr. 1(18), pp. 46-51. ISSN 1857-1727. DOI: https://doi.org/10.19261/cjm.2023.924 |
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Chemistry Journal of Moldova | |
Numărul 1(18) / 2023 / ISSN 1857-1727 /ISSNe 2345-1688 | |
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DOI:https://doi.org/10.19261/cjm.2023.924 | |
CZU: 638.135:[543.4+615.32] | |
Pag. 46-51 | |
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The chemical composition, antioxidant and antimicrobial activity of propolis ethanolic and water-ethanolic extracts from the central zone of Moldova have been investigated by GC-MS and liquid chromatography. There were found 20 amino acids, of which the most abundant are glutamic acid, alanine, leucine and isoleucine. The main constituents of the alcoholic extract are pinocembrin, n-heptacosan and naringenin. The aqueous-alcoholic extract was characterized by the content of sakuranin, 4-methoxy sakuranetin, caryophylline oxide, isocaryophylline oxide, trans-longipinocarveol. The propolis extracts exhibited strong antioxidant (53.7 mg ascorbic acid eq./g extract or 113.4 mg Trolox eq./g extract and 87.5 mg ascorbic acid eq./g extract or 162 mg Trolox eq./g extract for ethanol, and water-ethanol extract, respectively) and antimicrobial activity (from 0.0055 up to 0.07%), suggesting their potential as natural agents for therapeutic use. |
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Cuvinte-cheie amino acid, gas chromatography–mass spectrometry, liquid chromatography, Antifungal activity, antibacterial activity |
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