Synthesis, Structure, and Biological Activity of Mixed-Ligand Amine-Containing Copper(II) Coordination Compounds with 2-(2-Hydroxybenzylidene)-N-(prop-2-en-1-yl)hydrazinecarbothioamide

Gulya Aurelian; Graur Vasilii О.; Ulchina Ianina; Bourosh Pavlina; Smaglii Vadim; Garbuz Olga; Tsapkov Victor I.

Conţinutul numărului revistei

Articolul precedent

Articolul urmator

718

SM ISO690:2012

GULYA, Aurelian, GRAUR, Vasilii О., ULCHINA, Ianina, BOUROSH, Pavlina, SMAGLII, Vadim, GARBUZ, Olga, TSAPKOV, Victor I.. Synthesis, Structure, and Biological Activity of Mixed-Ligand Amine-Containing Copper(II) Coordination Compounds with 2-(2-Hydroxybenzylidene)-N-(prop-2-en-1-yl)hydrazinecarbothioamide. In: Russian Journal of General Chemistry, 2021, vol. 91, pp. 98-107. ISSN 1070-3632. DOI: https://doi.org/10.1134/S1070363221010114

EXPORT metadate:
Google Scholar
Crossref
CERIF

DataCite
Dublin Core

Russian Journal of General Chemistry

Volumul 91 / 2021 / ISSN 1070-3632 /ISSNe 1608-3350

Synthesis, Structure, and Biological Activity of Mixed-Ligand Amine-Containing Copper(II) Coordination Compounds with 2-(2-Hydroxybenzylidene)-N-(prop-2-en-1-yl)hydrazinecarbothioamide

DOI:https://doi.org/10.1134/S1070363221010114

Pag. 98-107

Gulya Aurelian¹, Graur Vasilii О.¹, Ulchina Ianina¹, Bourosh Pavlina², Smaglii Vadim³, Garbuz Olga¹⁴, Tsapkov Victor I.¹

¹ Moldova State University,
² Institute of Applied Physics,
³ Institute of Chemistry,
⁴ Institute of Zoology

Proiecte:

20.80009.8007.03 Noi substanțe cu potențial preventiv și terapeutic în baza compușilor naturali de origine vegetală și a matodelor moderne de sinteză organică

Disponibil în IBN: 6 aprilie 2021

Rezumat

Abstract: Сopper(II) nitrate reacts in ethanol with 2-(2-hydroxybenzylidene)-N-(prop-2-en-1-yl)hydrazinecarbothioamide H₂L in an 1 : 1 molar ratio to form the coordination compound Cu(HL)NO₃·H₂O. The introduction of amines [imidazole (Im), 3,5-dibromopyridine (3,5-Br₂Py), and 4-methylpyridine (4-Pic)] into the reaction mixture in a molar ratio 1 : 1 : 2 leads to the formation of CuA(HL)NO₃·nH₂O [A = Im, 3,5-Br₂Py, 4-Pic; n = 0, 3] complexes. The structure of the obtained compounds was determined by X-ray structural analysis. The synthesized complexes exhibit antimicrobial, antifungal, antioxidant, and anticancer activities.

Cuvinte-cheie
Amines, anticancer activity, Antimicrobial activity, Cu(II) coordination compounds, salicylaldehyde 4-allylthiosemicarbazone

Dublin Core Export

<?xml version='1.0' encoding='utf-8'?>
<oai_dc:dc xmlns:dc='http://purl.org/dc/elements/1.1/' xmlns:oai_dc='http://www.openarchives.org/OAI/2.0/oai_dc/' xmlns:xsi='http://www.w3.org/2001/XMLSchema-instance' xsi:schemaLocation='http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd'>
<dc:creator>Gulea, A.P.</dc:creator>
<dc:creator>Graur, V.O.</dc:creator>
<dc:creator>Ulchina, I.</dc:creator>
<dc:creator>Bouroş, P.N.</dc:creator>
<dc:creator>Smaglii, V.A.</dc:creator>
<dc:creator>Garbuz, O.S.</dc:creator>
<dc:creator>Ţapcov, V.I.</dc:creator>
<dc:date>2021-01-13</dc:date>
<dc:description xml:lang='en'><p>Abstract: Сopper(II) nitrate reacts in ethanol with 2-(2-hydroxybenzylidene)-N-(prop-2-en-1-yl)hydrazinecarbothioamide H<sub>2</sub>L in an 1 : 1 molar ratio to form the coordination compound Cu(HL)NO<sub>3</sub>&middot;H<sub>2</sub>O. The introduction of amines [imidazole (Im), 3,5-dibromopyridine (3,5-Br<sub>2</sub>Py), and 4-methylpyridine (4-Pic)] into the reaction mixture in a molar ratio 1 : 1 : 2 leads to the formation of CuA(HL)NO<sub>3</sub>&middot;nH<sub>2</sub>O [A = Im, 3,5-Br<sub>2</sub>Py, 4-Pic; n = 0, 3] complexes. The structure of the obtained compounds was determined by X-ray structural analysis. The synthesized complexes exhibit antimicrobial, antifungal, antioxidant, and anticancer activities.&nbsp;</p></dc:description>
<dc:identifier>10.1134/S1070363221010114</dc:identifier>
<dc:source>Russian Journal of General Chemistry  () 98-107</dc:source>
<dc:subject>Amines</dc:subject>
<dc:subject>anticancer activity</dc:subject>
<dc:subject>Antimicrobial activity</dc:subject>
<dc:subject>Cu(II) coordination compounds</dc:subject>
<dc:subject>salicylaldehyde 4-allylthiosemicarbazone</dc:subject>
<dc:title>Synthesis, Structure, and Biological Activity of Mixed-Ligand Amine-Containing Copper(II) Coordination Compounds with 2-(2-Hydroxybenzylidene)-N-(prop-2-en-1-yl)hydrazinecarbothioamide</dc:title>
<dc:type>info:eu-repo/semantics/article</dc:type>
</oai_dc:dc>