The application of the mineral fertilizers on the natural background of the chernozem leached after the preceding sunflower led to the increase of the autumn wheat production up to 6.32 t/ha. On average, for 9 yrs, wheat yields increased from 2.10 t/ha to 4.24 t/ha, obtaining an increase of 34-102%, compared to the non-fertilized variant. Phosphorus fertilization levels from 1.5 mg to 4.5 mg/100 g of mobile phosphorus soil led to wheat yields increase by 27-64%. The administration of nitrogen fertilizers in doses of 30-150 kg/ha on the background of P3.5K brought an increase of 27-67%. The wet gluten content in wheat grains increased from 14.4% to 40.8%. The maximum yield of gluten production per 1 ha was 154-160%. It has been established that in order to obtain a production of 4-6 t/ha of wheat on leached chernozem, the optimal level of mobile phosphorus in the soil is 3.0-3.5 mg/100 g of soil (Macighin method), and the optimal doses of nitrogen after the preceding sunflower are 90-120 kg/ha.