The article aims to define the role of “Markets” as a component of the entrepreneurial ecosystem, as well as to evaluate some indicators of this component in relation to the Republic of Moldova. The assessment was based on the results of a survey of entrepreneurs, carried out within the framework of the applied research project “Multidimensional assessment and development of the entrepreneurial ecosystem at the national and regional level in order to boost the SME sector in the Republic of Moldova” (2020-2023) in the period of June-October, 2022. For the “Markets” component, a survey of entrepreneurs showed a slight excess of negative estimates over positive ones. The market opportunities of enterprises are characterized by a fairly high level of competition in the domestic market, including from the informal sector, as well as a relatively high level of demand for goods/services in the domestic market. However, the practice of cooperation with other enterprises is still not sufficiently developed, in particular, cooperation between large enterprises and the SME sector is at a minimum level. The market access factor was assessed negatively by the majority of entrepreneurs, especially since access to both the CIS markets and the EU markets is particularly difficult at present.