The article substantiates the relevance of the promising direction of sustainable development of the national economy – clustering – an effective tool for increasing the competitive positions of regional industrial policy in foreign markets based on improving social, economic, investment, innovation, infrastructure, technological and environmental development directions, and their components. In this regard, the issues of integration in industrial policy occupy the main place both in business structures and in public authorities, civil institutions. The goal is to develop criteria for assessing the competitiveness management of agro-industrial clusters. The object of research is cooperative–integration (cluster) structures. The subject of the study is the components of the organizational and economic mechanism for managing the competitiveness of cooperative integration (cluster) structures. Research methods. The following methods were used in the research process: a systematic approach, comparison, logical generalization, analysis, and synthesis. Research results. The groups of factors contributing to and hindering the competitiveness management of regional cooperative productions are identified, contributing to the identification of regional advantages of creating priority industrial cooperative-integration industries.