Plant growth regulators (PGRs) are widely used in agriculture and horticulture to increase crop production. Conventional synthetic PGRs such as 2,4-dichlorophenoxyacetic acid having harmful effects on the environment and plant health [3], an important task for researchers is to develop alternative innovative plant growth regulators. Natural compounds extracted from plants or produced by bacteria rapidly degrading and being of limited use, PGRs based on syn-thetic analogs of natural substances or active pharmaceutical agents are considered to be more effective [3]. One of the natural compounds using as a building block in the development of new biologically active substances including PGRs is para-aminobenzoic acid (PABA). PABA is a well-known precursor of folic acid and exhibits a wide range of biological activities: anti-oxidant, antibacterial, antimutagenic, anticoagulant, protective against UV-irradiation [1]. It is also known about the role of PABA in plant thermotolerance and its action as chemical inducer of systemic acquired resistance against plant pathogens [1]. Some PABA derivatives have an auxin like effect. For example, PABA amides containing glycine and glutamic acid residues demonstrate growth stimulating activity due to an increase in the content of formyltetrahy-dropteroylglutamate (for Raphanus sativus and Triticum aestivum) [2]; homologous derivati-ves of PABA containing a phenylureide fragment stimulate the growth of monocotyledonous plants (for example, Triticum aestivum) [4]; and 2-hydroxyethylammonium salt of PABA has a stimulating effect on the growth and development of the root system of Arabidopsis thaliana [1]. Therefore, the purpose of the work is to obtain PABA derivatives and study their growth stimulating and protective activity on agricultural crops seeds.