Our paper aims to present, in general lines, the relationship of the Cantemirs with the visual arts, a relationship that has manifested itself in various forms. The first information regarding the filiation of this kin with the artistic-plastic expression is attested at Constantin Cantemir, lord of the Land of Moldavia. His son Dimitrie was not only an exceptional musician, but a gifted painter, who also had extensive knowledge in the field of architecture and sculpture. He got the most out of the mastery of technical and expressive means in his activities of practical creation. Dimitrie Cantemir's talent and artistic occupations were inherited by his descendants - Antioh, Maria and Ecaterina. The given paper comes to denote once again the intellectual depth of the Cantemirs and, at the same time, emphasizes the fact that the visual arts had been an organic part of the spiritual nourishment of this noble family for several generations, serving as a powerful means of aesthetic education and cultural formation in the spirit of the European Enlightenment.