Since the discovery of the effect of the behavior of ferromagnetic (Fe3O4) nanoparticles in 2007 by a group of researchers, nanoparticles showed intrinsic peroxidase-like activity, with catalytic behavior similar to horseradishperoxidase (HRP). A number of papers appeared devoted to similar properties for a number of other nanoparticles: CeO2, Ru, Pd, NiO etc [1-2]. In particular, depending on the acidity of the medium, magnetite nanoparticles as enzyme mimetics can exhibit both peroxidase and catalase properties. The chemical reactions driven by these two enzymes are: The term “nanozyme” was introduced to define nanomaterials with intrinsic enzyme-like activities. Nanozymes find applications in various fields, such as bioelectronics-sensor devices, biosynthesis, environmental protection [3]. We studied the catalase activity of the soil during the growth of sorghum treated with colloidal solutions of Fe3O4/PVP nanoparticles. Sorghum vulgare Alisiers was chosen as a test object. The test response was the length of the roots and shoots of the wheat. Catalase activity was determined by the Galustyan method by oxygen evolution. A colloidal solution Fe3O4/PVP magnetite nanoparticles in concentrations of 10, 25, 50 and 75 mg/kg of dry soil was used. An increase in catalase activity depending on the concentration of magnetite nanoparticles allows us to conclude about the synergistic effect of enzyme-like nanoparticles.