Social interest in natural mineral waters is determined by their impact on water-salt metabolism, therapeutic effect and the effectiveness of metabolic processes in the human body. At present, the most important deposits of Eurasian natural mineral waters have been discovered and studied, the chemical composition and physicochemical properties of water have been determined, and their medical and biological assessment has been carried out. However, studies of the composition and properties of newly discovered regional mineral waters with a view to assessing their therapeutic effect on human health remain very promising. The chemical composition of waters is determined by the processes of mixing waters of different horizons, such as carbon dioxide, fresh waters and highly mineralized relict sea waters. Natural waters are characterized by total mineralization, dissolved carbon dioxide, pH, electrical conductivity and other physicochemical parameters. On the Eurasian continent a large number of mineral water deposits are successfully exploited, the chemical composition of which is quite close to each other due to the genetic similarity of the geological conditions of their formation. Previously, we [1], on the basis of set theory and differential equations, developed a mathematical model linking a specific type of water with ionic composition and mineralization. According to the proposed model, the therapeutic properties of mineral waters are determined by the composition of anions forming water (chloride, sulphate, bicarbonate), whose properties determine the effectiveness of their effect on the chemical composition of human physiological fluids. The proposed mathematical model allowed, along with the classification of well-known Eurasian mineral waters, to identify newly discovered regional sources of natural waters for their conformity to approved Eurasian waters, and can also be recommended for organizing a monitoring system for developed fields for their use in balneological practice. Mineral water deposits are being developed on the territory of the Republic of Moldova, the chemical composition of which is quite close to each other due to the genetic similarity of the hydrogeological conditions of their formation. In the present work it is shown that the natural mineral waters of the Republic of Moldova are a collection of waters, for example, of the hydrocarbonate-chloride type (Soroka No. 1, Varnitsa unique), the hydrocarbonate-sulfate type (Chisinau, Aqualife, Gura Cainarului), the sulfate-hydrocarbonate type, (Resan, Cahul, Real, Lider) and evaluated their compliance with the mineral waters of Germany, Czech Republic, Italy, Spain and Romania.