| Conţinutul numărului revistei |
| Articolul precedent |
| Articolul urmator |
 817 0 |
 SM ISO690:2012KHOMENKO, Dmytro, DOROSHCHUK, Roman, RASPERTOVA, Ilona V., LOPEZ, Jesus Garcia, ORTIZ, Fernando Lopez, SHOVA, Sergiu, IEGOROV, Oleg, LAMPEKA, Rostyslav. Cascade reactions for constructing heterocycles containing a pyrimidino-pyrazino-pyrimidine core using 1,2,4-triazole scaffolds. In: Tetrahedron Letters, 2019, nr. 39(60), p. 0. ISSN 0040-4039. DOI: https://doi.org/10.1016/j.tetlet.2019.151089 |
| EXPORT metadate: Google Scholar Crossref CERIF DataCite Dublin Core |
 Tetrahedron Letters |
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| Numărul 39(60) / 2019 / ISSN 0040-4039 | ||||||
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| DOI:https://doi.org/10.1016/j.tetlet.2019.151089 | ||||||
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| Rezumat | ||||||
The regioselective cyclocondensation of aminoethyl-1,2,4-triazoles and glyoxal provides pentacyclic heterocycles in which two 7,8-dihydro-5H-6λ2-[1,2,4]triazolo[1,5-c]pyrimidine systems are connected through CH(OH) bridges generating a central piperazine-2,5-diol ring. The structure of the new compounds was elucidated based on 1H, 13C and 15N NMR spectroscopic methods. The molecular structure of the parent compound generated from aminoethyl-1,2,4-triazole was established by single crystal X-ray diffraction. |
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| Cuvinte-cheie 1, 2, 4-Triazole Cyclization Pyrazine Conformationally rigid |
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