As in most health care systems, health technologies made a significant contribution to improvements in quality of care in the Republic of Moldova in the last decades. However, there are currently no instruments in place to efficiently plan, manage and coordinate investments in health technology. The present work describes the assessment, evaluation and introduction of a web-based application with the objective to strengthen the Health Technology Management (HTM) in the country. The open source tool ―openMEDIS‖ was configured, adapted and successfully introduced in six pilot hospitals. The new management instrument has received good attention by the decision-makers at national and at regional level. As a next step, openMEDIS will be scaled-up to all maternities in the country to facilitate evidence-based planning in Perinatology.