Etiopathogenesis of acute community acquired pneumonia
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2019-06-24 13:27
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616.24-002-092-07-085 (1)
Patologia sistemului respirator. Tulburări ale organelor de respiraţie (334)
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NEAMŢU, Bogdan-M.; MATACUTA, Ioana; HADJIU, Svetlana. Etiopathogenesis of acute community acquired pneumonia. In: Buletin de Perinatologie. 2019, nr. 2(83), pp. 74-79. ISSN 1810-5289.
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Buletin de Perinatologie
Numărul 2(83) / 2019 / ISSN 1810-5289

Etiopathogenesis of acute community acquired pneumonia

CZU: 616.24-002-092-07-085
Pag. 74-79

Neamţu Bogdan-M.1, Matacuta Ioana1, Hadjiu Svetlana2
1 Lucian Blaga University Sibiu,
2 ”Nicolae Testemițanu” State University of Medicine and Pharmacy
Disponibil în IBN: 21 iunie 2019


Acute community pneumonia etiology is related to age and immune system status. Certain age groups (neonates, infants, ante-preschools, preschoolers, schoolchildren, adolescents, patients with severe immunosuppression) reveal particular aspects in immune defense mechanisms (macrophages, neutrophils, lymphocytes and eosinophils) and nonimmune responses (aerodynamic fi ltration of inhaled particle size, shape, electrostatic charge, cough refl ex, mucociliary clearance, lysozyme, complement, defensine). Firstly, this review tackles the main mechanisms involved in airway permeability, alveolar ventilation and perfusion impairments, gas exchange and cellular metabolism alterations aff ecting vital tissues and organs. Th en, the focus is on the age related pathogens interaction with the host defence systems, in diff erent age groups.