Personalized health care in general and personalized medical products in particular aim to provide the optimal diagnosis and treatment with the use of the right medicine, tools and devices to the right patient at the right time in order to meet well technical and clinical requirements as well as individual characteristics of each patient. This offer the increased effectiveness and better patient safety, and can obtain the best diagnosis and treatment quality. The design and development of personalized medical product is one of the most interesting areas for the last decades, especially from the time when Rapid Prototyping (RP) and Rapid Manufacturing (RM) were successfully applied for development of implants, surgical tools and medical devices for diagnosis and treatment. The main goal is to restore mobility and normal anatomic functionality of the joints affected by congenital and post-traumatic malformations, through the development of personalized implants based on 3D skeletal reconstruction from medical images.