The studied polyploid hybrids inherit the morpho-anatomical characters of generative organs differently, analogically to the features of leaf blade and petiole structure. The characters of apple flowers prevail in these hybrids, but their flowers are bigger. A distinguishing feature of the paternal triploid and diploid hybrids is the number of flowers in an inflorescence – from 1 to 4; solitary flowers predominate – 50-65%. The number of inflorescences with 2-3 flowers constitutes 31-47%, which allows us to conclude that these hybrid plants inherit this character from both genitors. The 75% of the flowers of diploids are solitary and only 25% are inflorescences with 2 flowers. In the tetraploids and paternal triploids, solitary flowers predominate (97-99 %) and inflorescences with 2 flowers are very rarely observed.   The triploid intergeneric hybrids quince x apple differ from other hybrid forms by the number of flowers in inflorescences and the flowering period, which coincides with the flowering of late varieties of apple. The quince varieties start flowering later and the pollen of apple varieties with late flowering period can be used to improve these hybrid forms. It has been established a directly proportional correlation between the polyploidy level and the size of the pollen grain. Pollen viability of tetraploids is higher (56-67%) than of triploids, which constitutes 3.1-10.2%. The studied tetraploids are distinguished from other hybrid forms by the high viability of the pollen, the larger size of pollen grains and cells from the zones and subzones of the pericarp. The pollen of diploids proved to be sterile in all variants. The paternal triploid hybrids inherit the characters of initial forms, mostly the characters of apple fruits (shape, taste and colour of the epicarp) but also specific features of quince (mostly solitary flowers – more than 50%, stable crops, presence of sclereids in fruit parenchyma). The studied distant hybrids differ in shape, size and intensity of fruit colour. The triploids’ fruits don’t contain seeds; few of them have 1-2 underdeveloped seeds, unlike tetraploid forms which contain 10-22 viable seeds in a fruit.  The pericarp of mature fruits of distant hybrids bears certain similarities in tissue zoning from outside to inside (epicarp, mezocarp differentiated into 4 subzones and endocarp) to the parental forms. The epicarp of a mature fruit is represented by single layered external epidermis covered by a relatively thick cuticle which constitutes 16.9-34.2 µm, of external-internal type, with the degree of spread from 1/3 up to 1/2 among epidermal cells. The epidermis is composed of polygonal parenchymal cells, tangentially elongated. The mezocarp is the middle tissue layer, the most voluminous part of the pericarp, made up of parenchymal cells. In the fruit mezocarp of the studied hybrids (similar to quince and apple), from outside to inside, there are 4 subzones which succeed one another easily without definite boundaries: the hypodermis, the external subzone of oval-rounded cells, the subzone of radial oval-elongated cells and the internal subzone of oval-rounded cells. The endocarp of the fruits of distant hybrids Cydonia x Malus is the internal histological zone, represented by the internal epidermis consisting of a layer of cells of 28-35 μm, well wrapped, elongated on the tangential axis and arranged in the form of parquet, with thickened cell walls. The studied progenies differ from each other and from other hybrid forms in the thickness of cuticle and parchment layer, the size of epidermal cells (tangential and radial) and parenchymal cells from the subzones of the mezocarp (hypodermis, the subzone of oval-rounded and oval-elongated cells), the density and arrangement of sclereids in mezocarp. In the paternal triploids, the uneven thickness of the cell walls of epidermal cells, the absence of sclereids in the external subzone of oval-rounded cells and the shape of endocarp cells typical of apple dominate in the structure of pericarp and the size and shape of cells from other subzones of the mezocarp was inherited intermediary. The tetraploids from other hybrid forms by larger pericarp cells are distinguished.   Our research confirms the similarities (dominance of characters of generative organs of apple) in the morpho-anatomical and biochemical peculiarities of vegetative organs and seeds of paternal triploid distant hybrids. The results of the morpho-anatomical research can be used to develop a program on fruit tree improvement and further testing of resistance of hybrids from (subfam. Pomoideae) fam. Rosaceae.