Campylobacter Jejuni infection remains one of the most common identified cause of acute gastroenteritis worldwide
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2021-10-18 20:12
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FLOREA, Natalia, MASOUD, Mohammad. Campylobacter Jejuni infection remains one of the most common identified cause of acute gastroenteritis worldwide. In: Microbial Biotechnology, 12-13 octombrie 2016, Chișinău. Chișinău, Republica Moldova: Institutul de Microbiologie şi Biotehnologie, 2016, Ediția 3, p. 61.
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Microbial Biotechnology
Ediția 3, 2016
Conferința "Microbial Biotechnology"
Chișinău, Moldova, 12-13 octombrie 2016

Campylobacter Jejuni infection remains one of the most common identified cause of acute gastroenteritis worldwide


Pag. 61-61

Florea Natalia, Masoud Mohammad
 
”Nicolae Testemițanu” State University of Medicine and Pharmacy
 
 
Disponibil în IBN: 13 martie 2019



Teza

Infection with Campylobacter jejuni is one of the most common causes of gastroenteritis worldwide. It occurs more frequently than infections caused by Salmonella species, Shigella species, or Escherichia coli O157: H7. In developed countries, the incidence of Campylobacter jejuni infections peaks during infancy and again during early adulthood. Although 14 species of Campylobacter have been identified, in the United States >99% of reported infections with Campylobacter are with C. jejuni [1, 2]. Therefore, this paper will be limited to a discussion of C. jejuni. In the treatment of Campylobacter infections, is preferred the antibiotic therapy with Azithromycin in a typical regimen of 500 mg/d for 3 days. Equally effective is Erythromycin, its resistance remains low and it can be used in pregnant women and children. Ciprofloxacin and tetracycline could be an alternative, but they cannot be used in children because of side effects. Unfortunately, the use of fluoroquinolones in animal feed by specialized animal breeding farms led to the worldwide emergence of fluoroquinolone-resistant Campylobacter strains [3]. This situation threatens consumer health and increase the percentage of complications caused by Campylobacter strains. Local complications of Campylobacter infections occur as a result of direct spread from the gastrointestinal tract and can include cholecystitis, pancreatitis, peritonitis, and massive gastrointestinal hemorrhage, septicemia, meningitis, urinary tract infections, and appendicitis [4]. A sizeable percentage of persons who are suffering from Campylobacter infections develop Guillain-Barre Syndrome, which causes neuromuscular paralysis. Miller Fisher Syndrome is another related neurological syndrome that can follow Campylobacteriosis, and is also caused by a triggered immune-response. Overall, there is no one factor that appears to cause a greater percentage of GBS cases other than Campylobacter infections. [5] In closing, we want to appeal to the common sense of farmers and feed manufacturers to stop using antibiotics. It is known that “It is much easier to prevent a disease than to treat it.”