The aim of this study is to present the function of the Inductively Coupled Plasma - Mass Spectrometry (ICP-MS), and the advantages in the multi-element analysis in comparison with other atomic spectroscopy instruments together with the results obtained in several trace elements in water samples of the Kavala area in order to explain their quality according to the council directive 98/83/EC. Using ICP-MS almost all the elements of periodic table can be measured from Li to U and simultaneously up to 35 elements in a sample within 3-4 min and with precision plus or minus 1-2% in a large scale from ppm to ppt, ppq. The analyst has the option of various programs of analysis: quantitative analysis, semi quantitative analysis, isotopic analysis and isotopic ratio. Its key applications are in the following areas: environmental, water, foods, semiconductors, metal alloys, clinical, pharmaceutical, consumer goods, forensic, geological, archeological, chemical, hydrocarbons, oils, nuclear, academic/research. Advanced hyphenated techniques allow the coupling of the ICP-MS with Laser Ablation (LA) to create a unique non-catastrophic system for direct solid sampling without dissolution, virtually in any material, that minimizes sample preparation time. We acknowledge the Erasmus+ program between the Technological Educational Institute of Eastern Macedonia and Thrace (TEI EMT), Kavala, Greece (2014-2016) and Dunărea de Jos University of Galati and the Erasmus program between TEI EMT, Kavala, Greece (2016-2018) and University of the Academy of Science of Moldova, Institute of Chemistry.