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SM ISO690:2012 PROCA, Nicolae, DANILESCU, Diana, COJUHARI, Maria, BUGOR, Kalina, BURDA, Tatiana. Particularităţi clinice şi paraclinice în ciroza biliară primară. In: Sănătate Publică, Economie şi Management în Medicină , 2014, nr. 5(56), pp. 82-85. ISSN 1729-8687. |
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Sănătate Publică, Economie şi Management în Medicină | ||||||
Numărul 5(56) / 2014 / ISSN 1729-8687 /ISSNe 2587-3873 | ||||||
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Pag. 82-85 | ||||||
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The aim of the study was to evaluate the clinical and paraclinical particularities in primary biliary cirrhosis (PBC). We performed a retrospective study of 40 patients, hospitalized in the Department of Hepatology: 37 women (92,5%) and 3 men (7,5%), with a mean age of 47 years. Onset of disease was asymptomatic in 10 (25,0%) patients and was manifestated by pruritus in 17 (42,5 %) patients. The most common symptoms of PBC at the time of the examination were: asthenia in 30 (75,0%) patients and pruritus in 22 (55,0%) patients. Hepatomegaly was detected in 34 (85,0%) patients, splenomegaly – in 21 (52,5%) patients and palmar erythema – in 4 (10,0%) patients. Often extrahepatic manifestations were: osteoporosis in 4 patients (10,0%), arthralgia 7 (17,5%) patients and pneumosclerosis in 7 (17,5%) patients. All patients had cholestasis syndrome. Antimitochondrial antibodies were determined in 32 (80,0%) patients, and increased IgM values in 28 (70,0%) patients. |
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Cuvinte-cheie primary biliary cirrhosis, pruritus, antimitochondrial antibodies |
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