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DUMITRAŞ, Tatiana; MATCOVSCHI, Serghei; DRĂGUŢĂ, Nelea; FLOREA, Natalia; CATRUC, V.; IGNATIUC, Elena. Relevanţa penicilinorezistenţei in vitro în cadrul pneumoniilor pneumococice. In: Curierul Medical. 2010, nr. 3(315), p. 167. ISSN 1875-0666.
|Numărul 3(315) / 2010 / ISSN 1875-0666|
Relevance of in Vitro Penicillin Resistance in Pneumococcal Pneumonia
The study included 250 patients aged between 18 and 59 years. The patients underwent clinical, biological, radiological, microbiological and
immunological examinations. The antibacterial sensitivity of the isolated stems of micro-organisms was tested by diffuse-metrical method and
were considered resistant if the penicillin inhibition zone diameter was less than 20 mm. Cases of S. pneumoniae pneumonias were analyzed
retrospectively to penicillin sensitivity. Pneumonias caused by penicillin sensitive S. pneumoniae frequently begins with a typical acute fever,
cough, stabbing chest pain, a more pronounced systemic inflammatory response, but a slower involution of clinical symptoms and suppurative
complications are more characteristic for community-acquired pneumonia caused by penicillin resistant S. pneumoniae.
penicillin resistance, S. pneumoniae