Anemia este un satelit constant al patologiei cronice renale, afectând circa 90% din numărul total de pacienţi. Una din consecinţele anemiei reprezintă disfuncţiile cardiovasculare. Din factorii ce infl uenţează răspunsul la tratamentul cu eritropoietină fac parte defi citul de fi er, dializa adecvată, calitatea dializatului, inclusiv impurităţile (cloramina), ce are o importanţă mare în inhibarea eritropoiezei.

Anaemia is a consistent finding in chronic renal disease, affecting up to 90% of patients, and the central role of anaemia in the development of cardiovascular dysfunction is now well established. Although iron deficiency is probably the most important factor affecting response to recombinant erytropoietin (Epo, epoetin), other factors are of significance, including dialysis adequacy. Additionally, water treatment and distribution,sterilizants and the quality of the dialysate in terms of trace elements (particularly chloramine) are of importance in relation to erythropoiesis inhibition.