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| Patologia sistemului digestiv. Tulburări ale tubului alimentar (1732) |
 SM ISO690:2012URSUL, Sergiu, COJOCARU, Victor, GUŢAN, Virgiliu, BOTEZATU, Alexandru, GUTIUM, Corina. Patofiziologia sindromului disfuncţiei multiple de organe în transplantul de ficat. In: Sănătate Publică, Economie şi Management în Medicină , 2016, nr. 4(68), pp. 94-96. ISSN 1729-8687. |
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| Sănătate Publică, Economie şi Management în Medicină | ||||||
| Numărul 4(68) / 2016 / ISSN 1729-8687 /ISSNe 2587-3873 | ||||||
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| CZU: 616.36-089.843-092.12 | ||||||
| Pag. 94-96 | ||||||
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MODS (multiple organ dysfunction syndrome) can develop in the postoperative period in patients with liver transplantation and drastically reduces the survival rate of recipients. Triggers involved in the occurrence of MODS (sepsis, shock of various etiologies, extracorporeal circulation, multiply transfused, large surgery, etc.) elicits a humoral and cell reply from the body. The clinical consequence of this humoral and cellular answer is a continuous process, constantly changing, including SIRS, CARS and MARS, which endangers the patient’s life. During the years 2013–2016 in Moldova were performed 19 surgeries for liver transplantation, which were included in the study, divided into two groups: the fi rst group – 7 patients who met criteria MODS, lot 2 – 12 without MODS criteria. Among the primary pathological aggression that could cause severe development in MODS were recorded: a) the preoperative porto-pulmonary syndrome in 2 patients, CID syndrome – 3 patients, cholestatic syndrome and severe hepatodepressive – 7 patients; b) intraoperative – massive haemorrhage in one patient; c) postoperative – massive hemorrhage 4, relaparatomie – 2, CID syndrome – 4, acute rejection – three recipient. In conclusion, the survival of recipients is largely influenced by the development of MODS syndrome in the postoperative period of liver transplantation. |
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| Cuvinte-cheie multiple organ dysfunction syndrome, recipient, liver transplantation |
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<?xml version='1.0' encoding='utf-8'?> <oai_dc:dc xmlns:dc='http://purl.org/dc/elements/1.1/' xmlns:oai_dc='http://www.openarchives.org/OAI/2.0/oai_dc/' xmlns:xsi='http://www.w3.org/2001/XMLSchema-instance' xsi:schemaLocation='http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd'> <dc:creator>Ursul, S.</dc:creator> <dc:creator>Cojocaru, V.I.</dc:creator> <dc:creator>Guţan, V.</dc:creator> <dc:creator>Botezatu, A.A.</dc:creator> <dc:creator>Gutium, C.</dc:creator> <dc:date>2016-08-31</dc:date> <dc:description xml:lang='en'><p><em>MODS (multiple organ dysfunction syndrome) can develop in the postoperative period in patients with liver transplantation and drastically reduces the survival rate of recipients. Triggers involved in the occurrence of MODS (sepsis, shock of various etiologies, extracorporeal circulation, multiply transfused, large surgery, etc.) elicits a humoral and cell reply from the body. The clinical consequence of this humoral and cellular answer is a continuous process, constantly changing, including SIRS, CARS and MARS, which endangers the patient’s life. During the years 2013–2016 in Moldova were performed 19 surgeries for liver transplantation, which were included in the study, divided into two groups: the fi rst group – 7 patients who met criteria MODS, lot 2 – 12 without MODS criteria. Among the primary pathological aggression that could cause severe development in MODS were recorded: a) the preoperative porto-pulmonary syndrome in 2 patients, CID syndrome – 3 patients, cholestatic syndrome and severe hepatodepressive – 7 patients; b) intraoperative – massive haemorrhage in one patient; c) postoperative – massive hemorrhage 4, relaparatomie – 2, CID syndrome – 4, acute rejection – three recipient. In conclusion, the survival of recipients is largely influenced by the development of MODS syndrome in the postoperative period of liver transplantation.</em></p></dc:description> <dc:description xml:lang='ru'><p><em>Синдром </em><em>MODS</em><em>, который может развиваться в послеоперационном периоде у больных с трансплантацией печени, является опасным осложнением, потому что резко может снижать выживаемость реципиентов. Триггеры возникновения </em><em>MODS</em><em> (сепсис, шок различной этиологии, искусственное кровообращение, многократные переливания, большая хирургия и т.д.) вызывают гуморальный и клеточный ответ организма. Этот гуморальный и клеточный ответ образуют непрерывный процесс, постоянно меняющийся, в том числе СИРС, КАРС и МАРС, которые ставят под угрозу жизнь пациента. За 2013-2016 годы в Молдове были проведены 19 операций по пересадке печени, которые были включены в исследование и разделены на две группы: первая группа – 7 больных, которые соответствовали критериям </em><em>MODS</em><em>, вторая группа – 12 пациентов без критериев </em><em>MODS</em><em>. Среди первичных патологических агрессий, которые могут привести к серьезному развитию </em><em>MODS</em><em>, были записаны: а) предоперационное – порто-легочный синдром у 2 больных, синдром ДВС – 3 пациента, холестатический синдром – 7; </em><em>b</em><em>) интраоперационной – массивное кровоизлияние у одного пациента; </em><em>c</em><em>) послеоперационной – массивное </em>1086кровоизлияние <em>– 4, реоперация – 2, синдром ДВС – 4, острое отторжение – у трех реципиента. В заключение отметим, что выживание получателей во многом зависит от развития синдрома </em><em>MODS</em><em> в послеоперационном периоде после трансплантации печени.</em></p></dc:description> <dc:source>Sănătate Publică, Economie şi Management în Medicină 68 (4) 94-96</dc:source> <dc:subject>multiple organ dysfunction syndrome</dc:subject> <dc:subject>recipient</dc:subject> <dc:subject>liver transplantation</dc:subject> <dc:title>Patofiziologia sindromului disfuncţiei multiple de organe în transplantul de ficat</dc:title> <dc:type>info:eu-repo/semantics/article</dc:type> </oai_dc:dc>
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