Au fost examinaţi 119 pacienţi cu hipertensiune arterială gradele I-II în asociere cu obezitatea,vârsta medie 49 ± 0,6 ani. Evaluarea complexă a pacienţilor a demonstrat că grupul de pacienţi hipertensivi în asociere cu obezitatea este neomogen: la 52,9% de pacienţi a fost constatată insulinorezistenţă (22,7% – diabet zaharat tip II; 12,6 % – toleranţă alterată la glucoză; 17,6% – valori glicemice în limitele normei în asociere cu hiperinsulinemie), la 47,1% nu s-au înregistrat modificări ale spectrului glucidic. În continuare pacienţii au fost examinaţi în funcţie de prezenţa insulinorezistenţei. La pacienţii hipertensivi obezi prezenţa insulinorezistenţei se asociază mai frecvent cu dislipidemia, manifestată prin reducerea HDL-colesterolului şi creşterea nivelului de LDL-colesterol, trigliceride, raporturilor colesterol-total/HDL-colesterol, LDL-colesterol/HDL-colesterol, ceea ce presupune un indice sporit de aterogenitate.

It was examined 119 patients with arterial hypertension of I – II degree in association with obesity the mean age 49± 0,6 years. The complex evaluation of patients established that the group of hypertensive patients in association with obesity wasn’t homogenous: in 52,9% of cases it was established insulin resistance (22,7% - diabetes mellitus type II; 12,6% - deteriorated tolerance to glucose; 17,6% - glicemic data were into normal limits in association with hyperinsulinemia) in 47,1% of cases weren’t observed any modifications of glicemic spectrum. Later on the patients were examined in function of insulin resistance. The presence of insulin resistance has been established at patients with arterial hypertension and obesity was associated more frequently with dislipidemia manifested with reduced contains of HDL-cholesterol and elevation of LDL-cholesterol and trigligerides, relations total cholesterol/HDLcholesterol,LDL-cholesterol/HDL-cholesterol, the fact implying an increased index of aterogenity.