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SM ISO690:2012 MIRON, Ana. Depistarea precoce a afectărilor inflamatorii, ischemice şi hemoragice la nou-născuţii prematuri şi la termen prin intermediul citokinelor proinflamatorii. In: Sănătate Publică, Economie şi Management în Medicină , 2008, nr. 3(25), pp. 51-58. ISSN 1729-8687. |
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Sănătate Publică, Economie şi Management în Medicină | ||||||
Numărul 3(25) / 2008 / ISSN 1729-8687 /ISSNe 2587-3873 | ||||||
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Pag. 51-58 | ||||||
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Proinflammatory citokines role in regulation of normal and affected cerebral function represent a frontier that rapidly develop in neuroscience. Cytokines are molecules that are
synthesized not only by the immune system, but also by cells in the central nervous system, including neurons, glia, and brain vascular cells. In the brain, cytokines can be neuroprotective or they can contribute to neurodegeneration. The role of cytokines in the regulation of normal and abnormal brain function represents a rapidly growing frontier in neuroscience. Cytokines are pleiotropic and redundant, and
they can modulate the effects of neurotransmitters and neuropeptides; thus, in order to understand the effects
of brain cytokines on apoptosis and toxicity, it is necessary to study the temporal and spatial expression of complex networks of cytokines, growth factors, neuropeptides, and
neurotransmitters. This effort is currently in progress in many centers. Modulation of cytokine function in the central nervous system represents a new therapeutic strategy for
neurodegeneration. |
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