The article presents the definition, purpose and objectives of clinical epidemiology. It describes the different aspects of clinical epidemiology (theoretical, methodological and practical) that should be included in the educational programs. The purposes of medical higher education institutes include the formation of competences on evaluation of the diagnostic and healing process effectiveness in clinical practice as well as the effectiveness of preventive and anti-epidemic measures. Nowadays it is necessary to prepare qualified specialists with relevant professional knowledge, skills and decision-maker abilities in order to use the methods of disease treatment and prevention according to the evidence-based medicine standards. Many leading medical educational organisations have introduced Сlinical Epidemiology in the compulsory course as one of the fundamental disciplines. Modern educational programs on the discipline of Epidemiology require the expansion of the teaching of Clinical Epidemiology both in the basic educational programs and in the selected disciplines.