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SM ISO690:2012 COVANTSEV, Serghei, CIOLAC, Dumitru. The role of mast cells in type i diabetes mellitus. In: Analele Ştiinţifice ale USMF „N. Testemiţanu”, 2013, nr. 1(14), pp. 60-64. ISSN 1857-1719. |
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Analele Ştiinţifice ale USMF „N. Testemiţanu” | ||||||
Numărul 1(14) / 2013 / ISSN 1857-1719 | ||||||
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Pag. 60-64 | ||||||
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The incidence of type I diabetes mellitus is rising 3-5% per year. The general prevalence of this disease ranges from 1.6 - 30.9% depending on the country. The modern field of diabetology proposes different mechanisms for development of the disorder. Still insulitis remains the main cause, ranging from 54 - 89%, confirming the autoimmune genesis of type I diabetes. Mast cells have a wide range of functions in the connective tissue that raise many questions about their putative role in type I diabetes. In this article is presented a review of studies which show mast cells involvement in the pathophysiology of diabetes. |
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