Introduction. Allergic diseases are recognized as a significant global public health problem. In most cases, allergic diseases appear in childhood, comprising a significant percentage of the workload of doctors who deal with children in primary care and pediatric departments in hospitals. Objective: determining the strategy for improving the specialized service provided to children with allergic diseases based on the detection of current barriers, problems and needs. Material and methods. The statistical data were analyzed, the aspects regarding the management of children with allergic diseases over the course of about 30 years, the data regarding the scientific research carried out in the last 25 years at the base of the Mother and Child Institute, of the training programs in pediatric allergology in USMF “Nicolae Testemitanu” Results. It was determined that about 35% of children up to 18 years of age have suffered or are suffering from one or more allergic reactions and illnesses. The specialized service is provided by 9 certified specialists in pediatric allergology at hospital level, consultative polyclinics with a coverage index of 1:65,000 children. Several scientific researches in pediatric allergology were carried out at the Mother and Child Institute in the years 1998-2018. Conclusions. Based on the studies carried out, three directions were identified in strengthening the National Strategy regarding the management of children with allergic pathology in the Republic of Moldova: I - Improving the clinical management of patients through early detection of patients, training of pre-university and postgraduate medical education staff, improving the availability of effective research diagnostic methods, improving the availability of quality and effective drugs for the administration of specific immunotherapy and biological therapy ; II - Improving the health system with the development of orders and provisions necessary to regulate the service at the national level; III - Consolidating the knowledge of the patient, the family and the community about the management of allergic pathology.