Being a highly vulnerable industry, tourism was one of the most affected sectors, suffering the greatest crisis on record. The article reveals the impact of the Covid-19 pandemic on the tourism industry in the Republic of Moldova. There were explored the effects of the pandemic on tourism in the country and analysed the current situation in hospitality and tourism industry compared to the pre-pandemic period. The analysis showed that while the world saw an unprecedent fall in international tourism, domestic tourism has shown positive signs in the market. Also, it was highlighted that the tourism industry is undergoing changes, being mainly affected by economic factors, geopolitical situation and technological advancements. Main trends and challenges for tourism development in the Republic of Moldova were identified.