The aim of this study was to analyze the structure of non-cardiac pathology in patients with negative cardiac remodeling over 1 year after coronary revascularization. Material and Methods: The study included 87 patients (55 men and 32 women) after coronary revascularization who received treatment according to international guidelines for secondary prevention. Echocardiographic examination was performed initially and over 12 months after coronary revascularization. We evaluated: left atrium dimensions (LA), left ventricular parameters: left ventricular end-sistolic (LVES, mm), end-diastolic diameter (LVED, mm), end-systolic volume (ESV, ml), end-diastolic volume (EDV, ml); longitudinal diameter in systole and diastole, sphericity index at systole (SIS), at diastole (SID), relative wall thickness (RWT), ejection fraction (LVEF). Depending on the dynamic of cardiac remodeling all patients were divided in two groups: group 1- patients with negative dynamic parameters of cardiac remodeling (n = 35), group 2 -patients without negative dynamics (n = 52). The presence of non-cardiac pathology was analyzed in each group in accordance to the method Charlson. Results: Charlson index of comorbidity was higher in group 1- 4,9 vs 2,3 in group 2 (p < 0,001). Patients in group 1 had more than one non-cardiac pathology; were older (mean age 63,8 ± 1,2 vs 57,4 ± 1,1) and had an advanced degree of heart failure (functional class NYHA III vs II). Conclusion: The negative dynamic of heart remodeling after coronary revascularization was adversely influenced b y t he p resence o f m ultiple non-cardiac comorbidities.